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manu-tej/README.md

Manu Tej Sharma Arrojwala

Bioinformatics scientist — 8 years applying ML and software engineering to biology, 6+ in oncology drug discovery at Arcus Biosciences (tumor-immune phenotyping, neoantigen & TCR workflows, multi-omics platforms and pipelines).

I build biology agents and the evaluations that test whether they run real analyses with calibrated uncertainty — systems that recognize when the evidence isn't there and stop, instead of returning a confident answer that's quietly wrong.

Selected work

  • coscientist — multi-agent hypothesis tournament with a truth-tracking eval harness grounded against GPQA-bio
  • ai-scientists — trust profile of biology agents on BiomniBench-DA (contamination, calibration, refusal, benchmark validity)
  • methods-graph — bioinformatics methods knowledge graph (EDAM + nf-core + BioContainers on Kùzu)
  • dogma — graph-grounded bioinformatics method guidance in the IDE

🔗 manu-tej.github.io

Pinned Loading

  1. Fish_counter Fish_counter Public

    Using DeepLabCut to count fishes and map their behaviour

    Python 3

  2. Depth_analyzer Depth_analyzer Public

    Tool for finding bower regions and to find depth changes in it

    Python 1

  3. Kinect2 Kinect2 Public

    Code to collect and analyze data for sand bowers built by Lake Malawi cichlids

    Python