@@ -297,3 +297,212 @@ datasets:
297297 - drug
298298 - drug descriptor
299299 - experiments
300+ cptac :
301+ description : Simplified and Unified Access to Cancer Proteogenomic Data
302+ references :
303+ - citation : Lindgren, C. M., Adams, D. W., Kimball, B., Boekweg, H.,
304+ Tayler, S., Pugh, S. L., & Payne, S. H. (2021).
305+ Simplified and Unified Access to Cancer Proteogenomic Data. Journal of proteome research,
306+ 20(4), 1902–1910. https://doi.org/10.1021/acs.jproteome.0c00919
307+ doi : https://doi.org/10.1021/acs.jproteome.0c00919
308+ modalities :
309+ - transcriptomics
310+ - proteomics
311+ - mutations
312+ - copy_number
313+
314+ ctrpv2 :
315+ description : " "
316+ references :
317+ - citation : Rees, M. G., Seashore-Ludlow, B., Cheah, J. H., Adams, D. J., Price,
318+ E. V., Gill, S., Javaid, S., Coletti, M. E., Jones, V. L., Bodycombe, N. E., Soule,
319+ C. K., Alexander, B., Li, A., Montgomery, P., Kotz, J. D., Hon, C. S., Munoz, B., Liefeld,
320+ T., Dančík, V., Haber, D. A., … Schreiber, S. L. (2016).
321+ Correlating chemical sensitivity and basal gene expression reveals mechanism of action. Nature chemical biology,
322+ 12(2), 109–116. https://doi.org/10.1038/nchembio.1986
323+ doi : https://doi.org/10.1038/nchembio.1986
324+ - citation : Seashore-Ludlow, B., Rees, M. G., Cheah, J. H., Cokol, M., Price, E. V., Coletti,
325+ M. E., Jones, V., Bodycombe, N. E., Soule, C. K., Gould, J., Alexander, B., Li, A., Montgomery,
326+ P., Wawer, M. J., Kuru, N., Kotz, J. D., Hon, C. S., Munoz, B., Liefeld, T., Dančík, V., … Schreiber,
327+ S. L. (2015). Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset.
328+ Cancer discovery, 5(11), 1210–1223. https://doi.org/10.1158/2159-8290.CD-15-0235
329+ doi : https://doi.org/10.1158/2159-8290.CD-15-0235
330+ - citation : Basu, A., Bodycombe, N. E., Cheah, J. H., Price, E. V., Liu, K., Schaefer, G. I.,
331+ Ebright, R. Y., Stewart, M. L., Ito, D., Wang, S., Bracha, A. L., Liefeld, T., Wawer, M.,
332+ Gilbert, J. C., Wilson, A. J., Stransky, N., Kryukov, G. V., Dancik, V., Barretina, J.,
333+ Garraway, L. A., … Schreiber, S. L. (2013).
334+ An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules.
335+ Cell, 154(5), 1151–1161. https://doi.org/10.1016/j.cell.2013.08.003
336+ doi : https://doi.org/10.1016/j.cell.2013.08.003
337+ modalities :
338+ - transcriptomics
339+ - proteomics
340+ - mutations
341+ - copy_number
342+ - drugs
343+
344+ fimm :
345+ description : " "
346+ references :
347+ - citation : Mpindi, J. P., Yadav, B., Östling, P., Nevedomskaya, E., Tuomela, J.,
348+ Aittokallio, T., & Wennerberg, K. (2016). Consistency in drug response profiling. Nature, 540(7631), E5–E6.
349+ https://doi.org/10.1038/nature20171
350+ doi : https://doi.org/10.1038/nature20171
351+ - citation : Pemovska, T., Kontro, M., Yadav, B., Edgren, H., Eldfors, S., Szwajda, A., Almusa, H., Bespalov,
352+ M. M., Ellonen, P., Elonen, E., Gjertsen, B. T., Karjalainen, R., Kulesskiy, E., Lagström, S., Lehto, A., Lepistö, M.,
353+ Lundán, T., Majumder, M. M., Marti, J. M., Mattila, P., … Wennerberg, K. (2013).
354+ Individualized systems medicine strategy to tailor treatments for patients with chemorefractory acute myeloid leukemia.
355+ Cancer discovery, 3(12), 1416–1429. https://doi.org/10.1158/2159-8290.CD-13-0350
356+ doi : https://doi.org/10.1158/2159-8290.CD-13-0350
357+ modalities :
358+ - transcriptomics
359+ - proteomics
360+ - mutations
361+ - copy_number
362+ - drugs
363+
364+ gcsi :
365+ description : " "
366+ references :
367+ - citation : Haverty, P. M., Lin, E., Tan, J., Yu, Y., Lam, B., Masoudi, H., Zhang, R.,
368+ Zhu, X., Ding, L., Swanson, K. D., Watanabe, C., Yang, X., Li, L., Li, M., Liang, H.,
369+ Lin, W., Lin, Y., Liu, J., Luo, J., Ma, Y., … Liang, H. (2016). Reproducible pharmacogenomic profiling of cancer cell line panels.
370+ Nature, 533(7603), 333–337. https://doi.org/10.1038/nature17987
371+ doi : https://doi.org/10.1038/nature17987
372+ - citation : Klijn, C., Durinck, S., Stawiski, E. W., Haverty, P. M., Jiang, Z., Liu, H.,
373+ Degenhardt, J., Mayba, O., Gnad, F., Liu, J., Pau, G., Reeder, J., Cao, Y., Mukhyala, K.,
374+ Selvaraj, S. K., Yu, M., Zynda, G. J., Brauer, M. J., Wu, T. D., Gentleman, R. C., … Zhang, Z. (2015).
375+ A comprehensive transcriptional portrait of human cancer cell lines. Nature biotechnology, 33(3), 306–312.
376+ https://doi.org/10.1038/nbt.3080
377+ doi : https://doi.org/10.1038/nbt.3080
378+ modalities :
379+ - transcriptomics
380+ - proteomics
381+ - mutations
382+ - copy_number
383+ - drugs
384+
385+ gdscv1 :
386+ description : " "
387+ references :
388+ - citation : Garnett, M. J., Edelman, E. J., Heidorn, S. J., Greenman, C. D., Dastur, A., Lau,
389+ K. W., Greninger, P., Thompson, I. R., Luo, X., Soares, J., Liu, Q., Iorio, F., Surdez, D.,
390+ Chen, L., Milano, R. J., Bignell, G. R., Tamura, K., Gaasenbeek, M., Mukherjee, S.,
391+ Berger, M. F., … McDermott, U. (2012). Systematic identification of genomic markers of drug sensitivity in cancer cells.
392+ Nature, 483(7391), 570–575. https://doi.org/10.1038/nature11005
393+ doi : https://doi.org/10.1038/nature11005
394+ - citation : Iorio, F., Knijnenburg, T. A., Vis, D. J., Bignell, G. R., Menden, M. P., Schubert, M., Aben, N.,
395+ Gonçalves, E., Barthorpe, S., Lightfoot, H., Cokelaer, T., Greninger, P., van Dyk, E., Chang, H., de Silva,
396+ H., Heyn, H., Deng, X., Egan, R. K., Liu, Q., Mironenko, T., … Garnett, M. J. (2016).
397+ A Landscape of Pharmacogenomic Interactions in Cancer. Cell, 166(3), 740–754. https://doi.org/10.1016/j.cell.2016.06.017
398+ doi : https://doi.org/10.1016/j.cell.2016.06.017
399+ - citation : Yang, W., Soares, J., Greninger, P., Edelman, E. J., Lightfoot, H., Forbes, S., Bindal, N., Beare, D.,
400+ Smith, J. A., Thompson, I. R., Ramaswamy, S., Futreal, P. A., Haber, D. A., Stratton, M. R., Benes, C., McDermott, U.,
401+ & Garnett, M. J. (2013). Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells.
402+ Nucleic acids research, 41(Database issue), D955–D961. https://doi.org/10.1093/nar/gks1111
403+ doi : https://doi.org/10.1093/nar/gks1111
404+ modalities :
405+ - transcriptomics
406+ - proteomics
407+ - mutations
408+ - copy_number
409+ - drugs
410+
411+ gdscv2 :
412+ description : " "
413+ references :
414+ - citation : Garnett, M. J., Edelman, E. J., Heidorn, S. J., Greenman, C. D., Dastur, A., Lau,
415+ K. W., Greninger, P., Thompson, I. R., Luo, X., Soares, J., Liu, Q., Iorio, F., Surdez, D.,
416+ Chen, L., Milano, R. J., Bignell, G. R., Tamura, K., Gaasenbeek, M., Mukherjee, S.,
417+ Berger, M. F., … McDermott, U. (2012). Systematic identification of genomic markers of drug sensitivity in cancer cells.
418+ Nature, 483(7391), 570–575. https://doi.org/10.1038/nature11005
419+ doi : https://doi.org/10.1038/nature11005
420+ - citation : Iorio, F., Knijnenburg, T. A., Vis, D. J., Bignell, G. R., Menden, M. P., Schubert, M., Aben, N.,
421+ Gonçalves, E., Barthorpe, S., Lightfoot, H., Cokelaer, T., Greninger, P., van Dyk, E., Chang, H., de Silva,
422+ H., Heyn, H., Deng, X., Egan, R. K., Liu, Q., Mironenko, T., … Garnett, M. J. (2016).
423+ A Landscape of Pharmacogenomic Interactions in Cancer. Cell, 166(3), 740–754. https://doi.org/10.1016/j.cell.2016.06.017
424+ doi : https://doi.org/10.1016/j.cell.2016.06.017
425+ - citation : Yang, W., Soares, J., Greninger, P., Edelman, E. J., Lightfoot, H., Forbes, S., Bindal, N., Beare, D.,
426+ Smith, J. A., Thompson, I. R., Ramaswamy, S., Futreal, P. A., Haber, D. A., Stratton, M. R., Benes, C., McDermott, U.,
427+ & Garnett, M. J. (2013). Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells.
428+ Nucleic acids research, 41(Database issue), D955–D961. https://doi.org/10.1093/nar/gks1111
429+ doi : https://doi.org/10.1093/nar/gks1111
430+ modalities :
431+ - transcriptomics
432+ - proteomics
433+ - mutations
434+ - copy_number
435+ - drugs
436+
437+ pancpdo :
438+ description : " "
439+ references :
440+ - citation : Tiriac, H., Belleau, P., Engle, D. D., Plenker, D., Deschênes, A., Somerville, T. D. D.,
441+ Froeling, F. E. M., Burkhart, R. A., Denroche, R. E., Jang, G.-H., Miyabayashi, K., Young, C. M.,
442+ Patel, H., Shah, M., Sanghvi, R., Goetz, A. B., Lowder, C. Y., Martello, L., Driehuis, E., LeComte, N.,
443+ … Shen, M. (2018). Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer.
444+ Cancer discovery, 8(9), 1112–1129. https://doi.org/10.1158/2159-8290.CD-18-0349
445+ doi : https://doi.org/10.1158/2159-8290.CD-18-0349
446+ modalities :
447+ - transcriptomics
448+ - mutations
449+ - copy_number
450+ - drugs
451+
452+ sarcpdo :
453+ description : " "
454+ references :
455+ - citation : Al Shihabi, A., Tebon, P. J., Nguyen, H. T. L., Chantharasamee, J., Sartini, S.,
456+ Davarifar, A., Jensen, A. Y., Diaz-Infante, M., Cox, H., Gonzalez, A. E., Norris, S., Sperry, J.,
457+ Nakashima, J., Tavanaie, N., Winata, H., Fitz-Gibbon, S. T., Yamaguchi, T. N., Jeong, J. H.,
458+ Dry, S., Singh, A. S., … Soragni, A. (2024). The landscape of drug sensitivity and resistance in sarcoma.
459+ Cell Stem Cell, 31(10), 1524–1542.e4. https://doi.org/10.1016/j.stem.2024.08.010
460+ doi : https://doi.org/10.1016/j.stem.2024.08.010
461+ modalities :
462+ - transcriptomics
463+ - mutations
464+ - drugs
465+
466+ crcpdo :
467+ description : " "
468+ references :
469+ - citation : van de Wetering, M., Francies, H. E., Francis, J. M., Bounova, G., Iorio, F., Pronk, A., van Houdt, W.,
470+ van Gorp, J., Taylor-Weiner, A., Kester, L., McLaren-Douglas, A., Blokker, J., Jaksani, S., Bartfeld, S., Volckman,
471+ R., van Sluis, P., Li, V. S., Seepo, S., Sekhar Pedamallu, C., Cibulskis, K., … Clevers, H. (2015).
472+ Prospective derivation of a living organoid biobank of colorectal cancer patients.
473+ Cell, 161(4), 933–945. https://doi.org/10.1016/j.cell.2015.03.053
474+ doi : https://doi.org/10.1016/j.cell.2015.03.053
475+ modalities :
476+ - transcriptomics
477+ - mutations
478+ - copy_number
479+ - drugs
480+
481+ liverpdo :
482+ description : " "
483+ references :
484+ - citation : Ji, S., Feng, L., Fu, Z., Wu, G., Wu, Y., Lin, Y., Lu, D., Song, Y., Cui, P., Yang, Z.,
485+ Sang, C., Song, G., Cai, S., Li, Y., Lin, H., Zhang, S., Wang, X., Qiu, S., Zhang, X., Hua, G., … Gao, Q. (2023).
486+ Pharmaco-proteogenomic characterization of liver cancer organoids for precision oncology. Science translational medicine,
487+ 15(706), eadg3358. https://doi.org/10.1126/scitranslmed.adg3358
488+ doi : https://doi.org/10.1126/scitranslmed.adg3358
489+ modalities :
490+ - transcriptomics
491+ - mutations
492+ - copy_number
493+ - drugs
494+
495+ novartispdx :
496+ description : " "
497+ references :
498+ - citation : Gao, H., Korn, J. M., Ferretti, S., Monahan, J. E., Wang, Y., Singh, M., Zhang, C., Schnell, C.,
499+ Yang, G., Zhang, Y., Balbin, O. A., Barbe, S., Cai, H., Casey, F., Chatterjee, S., Chiang, D. Y., Chuai, S.,
500+ Cogan, S. M., Collins, S. D., Dammassa, E., … Sellers, W. R. (2015).
501+ High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response.
502+ Nature medicine, 21(11), 1318–1325. https://doi.org/10.1038/nm.3954
503+ doi : https://doi.org/10.1038/nm.3954
504+ modalities :
505+ - transcriptomics
506+ - mutations
507+ - copy_number
508+ - drugs
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