diff --git a/README.md b/README.md
index c7f0ac9..a4056d9 100644
--- a/README.md
+++ b/README.md
@@ -26,6 +26,9 @@ MobiDB-lite is also available as Docker container [MobiDB-lite_docker](https://g
 
 
 ## Installation
+
+Supported Python versions: >=3.11,<3.15
+
 You can use the tool simply cloning this repo and running `__main__.py` Python script. 
 which implements a command line interface.
 To avoid import errors you need to add the source root folder 
@@ -38,13 +41,26 @@ in this case.
 
 From GitHub:
 
-    git clone https://github.com/BioComputingUP/MobiDB-lite.git
-    pip install .
+```bash
+git clone https://github.com/BioComputingUP/MobiDB-lite.git
+
+# one-off
+python3 -m venv .venv
 
-To install the dependencies:  
+source .venv/bin/activate
+    
+pip install .
+```
+
+### How to install MobiDB-lite using Conda?
 
-    pip install -r requirements.txt
+You can create a Conda environment and install MobiDB-lite using the following commands:
 
+```bash
+conda create -n mobidb_lite python=3.12
+conda activate mobidb_lite
+pip install .
+```
 
 ## Usage
 
diff --git a/pyproject.toml b/pyproject.toml
index c079f94..50160ba 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -13,15 +13,16 @@ authors = [
   {name = "Damiano Piovesan", email = "damiano.piovesan@unipd.it"},
   {name = "Mahta Mehdiabadi", email = "mahta.mehdiabadi@studenti.unipd.it"}
 ]
-requires-python = ">=3.12.3"
-dependencies = []
-
-[project.optional-dependencies]
-nu = [
+requires-python = ">=3.11.3,<3.15"
+dependencies = [
+  "joblib >= 1.5.2",
+  "numba >= 0.61.2",
+  "pandas >= 2.3.2",
   "scikit-learn >= 1.4.2",
-  "numba >= 0.59.1"
 ]
 
+[project.optional-dependencies]
+
 [tool.setuptools.packages.find]
 where = ["src"]
 namespaces = false
diff --git a/requirements.txt b/requirements.txt
index 823b71f..371439d 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -1,6 +1,4 @@
 joblib==1.5.2
 numba==0.61.2
-numpy==2.3.2
 pandas==2.3.2
-scikit-learn==1.4.2
-setuptools==59.6.0
+scikit-learn==1.4.2
\ No newline at end of file